Weleda presents daacro Statistics on Neurodoron®
Results of a post-hoc analysis were presented at the European Congress for Integrative Medicine 2016 in Budapest: a clinical trial with neurodoron® in patients with nervous exhaustion.
In September 2016, Rebecca Hufnagel, clinical research – medical field at Weleda AG, presented a clinical study sponsored by the company and conducted by emovis GmbH, Berlin. We performed a post-hoc analysis with the data:
154 probands (70 % female, average age 53 years) with states of nervous exhaustion (ICD: F48.0 Neurasthenia) were investigated in a monocentric, randomized, double-blind clinical study. Over a time period of 6 weeks, the probands took a tablet (Neurodoron or placebo) three times daily. The study protocol stipulated three examinations (baseline, 2 and 6 weeks later), at which mental state was assessed.
Initially, the study analysis revealed no positive effect of Neurodoron. As a result, daacro conducted a detailed exploratory analysis. Positive effects of Neurodoron were able to be demonstrated on the symptom level in particular. On 10 of 12 scales, reduction of symptom severity was more pronounced in the Neurodoron group than in the placebo group. The two most important symptoms, irritability and nervousness, even decreased significantly in the Neurodoron group, when compared to the placebo group.
Positive tendencies could also be found on further scales: During the intervention, the Neurodoron group showed a significantly more pronounced increase of happiness and a significantly stronger improvement on the physical sum scale of the SF36.
Probands in the Neurodoron group evaluated the substance’s effect on the progression of symptoms significantly more often as “large to very large” than the placebo group. Independently, the physician also evaluated the effectiveness of the substance significantly more often as “good to very good” in the Neurodoron group.
These results, which were first able to be revealed after a differentiated post-hoc analysis of the data, document the great importance of intraindividual data analyses – especially in the fields of naturopathy, nutritional supplements and herbal medicines.