Every person is individual, each having a unique medical history.
There are many methods available to physicians when dealing with stress-related health disorders.
neuropattern™ is a new diagnostic test that was also recently developed in Trier. It provides a comprehensive assessment of neuroendocrine, psychosocial, and physical health interactions that emanate from the brain and body under stress.
neuropattern™ is used to differentiate endophenotypes in patients with similar symptomatology. Thus, this the procedure is particularly suited for individualised diagnostics and pharmacogenetic studies.
Every person is individual, each having a unique medical history. There are many methods available to physicians when dealing with stress-related health disorders. These are time-consuming and expensive. neuropattern™ synthesises knowledge from basic research focusing on the three fundamental stress systems: work systems, energy supply systems and regeneration systems. These three systems are illustrated with the help of the neuropattern™ stress triangle, which identifies imbalances and reveals the causes of psychological and somatic symptoms. This is not only helpful when communicating the results to the patient, who receives an understandable “disease model” and recognizes why selected psychological and medical interventions are advisable. In drug research, the call for personalized treatment approaches is growing.
In drug research, the call for personalized treatment approaches is growing. With the neuropattern™ stress diagnostics system, endophenotyping can be conducted in studies, allowing characteristic profiles and with them specific subgroups of patients or probands to be identified. neuropattern™ measures biological signals as well as psychological and bodily stress reactions. After a physician takes the patient’s/proband’s medical history, he or she receives the neuropattern™ test set and takes the rest of the measurements at home. Alongside specially developed questionnaires, the test set includes 16 saliva collection vessels for the measurement of the stress hormone cortisol in saliva, a low dose of dexamethasone and a portable ECG. The ECG assesses heart rate variability, allowing an evaluation of the regulatory ability of the autonomic nervous system. The analysis of all the collected patient data provides an informed foundation for further treatment of the patient.